Understanding the lethal variant of prostate cancer: power of examining extremes.
نویسندگان
چکیده
Small cell prostate carcinoma is a lethal variant of castration-resistant prostate cancer. Beltran and colleagues identified overexpression and amplification of both aurora kinase A (AURKA) and the MYCN proto-oncogene in the small cell prostate carcinomas and propose Aurora kinase A as a potential therapeutic target in this disease subset.
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ورودعنوان ژورنال:
- Cancer discovery
دوره 1 6 شماره
صفحات -
تاریخ انتشار 2011